Pyrimidine nucleosides
Medchemexpress LLC 3'-Deoxycytidine | 7057-33-2 | 98.0% | 227.22 | 25 MG
3'-Deoxycytidine (4-Amino-1-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one) is a purine nucleoside analogue.
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
- Intended for research use only
Medchemexpress LLC 3'-Deoxycytidine | 7057-33-2 | 98.0% | 227.22 | 50 MG
4-Amino-1-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (3'-Deoxycytidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
- Functions as a purine nucleoside analogue.
- Demonstrates broad antitumor activity.
- Targets indolent lymphoid malignancies.
- Inhibits DNA synthesis.
- Induces apoptosis.
Medchemexpress LLC 3′-Deoxyuridine | 7057-27-4 | 98.0% | 228.20 | 1 ML
3′-Deoxyuridine is a potential anticancer and antiviral agent. It has been shown to inhibit bovine diarrhea virus (BVDV) production.
- Potential anticancer agent.
- Potential antiviral agent, inhibiting bovine diarrhea virus (BVDV) production.
Medchemexpress LLC Deoxycytidine triphosphate disodium | 102783-51-7 | 99.0% | 511.12 | 5 MG
Deoxycytidine triphosphate (dCTP) disodium is a nucleoside triphosphate that contains the pyrimidine base cytosine. It is for research use only and not sold to patients.
- Solid appearance
- White to off-white color
- Stored at -20°C, protected from light, and under nitrogen
- Soluble in H2O at 125 mg/mL (244.56 mM)
Medchemexpress LLC Deoxycytidine triphosphate disodium | 102783-51-7 | 99.0% | 511.12 | 100 MG
Deoxycytidine triphosphate (dCTP) disodium is a nucleoside triphosphate that contains the pyrimidine base cytosine. It is for research use only and not sold to patients. This product is suitable for:
- Oligonucleotides
- Nucleotide analogs
- Cytidine nucleotide
- Cell cycle/DNA damage research
- DNA/RNA synthesis research
Medchemexpress LLC 3'-Deoxycytidine | 7057-33-2 | 98.0% | 227.22 | 10 MG
3'-Deoxycytidine is a purine nucleoside analogue (4-Amino-1-((2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one) with broad antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms involve inhibition of DNA synthesis and induction of apoptosis.
- Inhibits replication of S180 cell line in vitro with an ED50 of 15 μM.
- Inhibits replication of CCRF-CEM cell line in vitro with an ED50 of 25 μM.
- Inhibits replication of L1210 cell line in vitro with an ED50 of 5 μM.
- Inhibits replication of P388 cell line in vitro with an ED50 of 2.5 μM.
Chem-Impex International, Inc. 5-Iodo-2'-deoxyuridine | 54-42-2 | MFCD00134656 | 25G
5-Iodo-2'-deoxyuridine, 54-42-2, MFCD00134656, 25G
Sigma Aldrich Fine Chemicals Biosciences 5 Bromo 2 deoxyuridine 5 t5MG
5-Bromo-2AE-deoxyuridine 5AE-triphosphate is used for incorporation into DNA for studying normal and tumor cell proliferation profiles.
Apexbio Technology LLC 2-Deoxyuridine 5-monophosphate disodium 42155-08-8 250mg
2-Deoxyuridine 5-monophosphate disodium (CAS 42155-08-8) is a nucleotide analog recognized as a natural substrate for thymidylate synthase (TS) TS catalyzes the methylation of this compound utilizing 5 10-methylenetetrahydrofolate as a methyl donor to generate deoxythymidine 5-monophosphate (dTMP) This enzymatic conversion constitutes an essential step in the de novo synthesis of thymidine nucleotides required for DNA replication 2-Deoxyuridine 5-monophosphate disodium is widely employed in studies exploring DNA synthesis the thymidylate biosynthetic pathway and the regulation of nucleotide metabolism
Cayman Chemical 2'-Fluoro-2'-deoxyuridine, Purity: ≥98%, CAS: 784-71-4, 10 mg
A derivative of uridine; hepatitis C polyU/UC RNA strands containing 2'-FdU bind to RIG-I but do not activate RIG-I signaling in a reporter assay using Huh7 cells; has been used as a starting material in the synthesis of RSV polymerases inhibitors
Cayman Chemical 2'-Fluoro-2'-deoxyuridine, Purity: ≥98%, CAS: 784-71-4, 25 mg
A derivative of uridine; hepatitis C polyU/UC RNA strands containing 2'-FdU bind to RIG-I but do not activate RIG-I signaling in a reporter assay using Huh7 cells; has been used as a starting material in the synthesis of RSV polymerases inhibitors
Cayman Chemical 5-Formyl-2'-deoxyuridine, Purity: ≥95%, CAS: 4494-26-2, 50 mg
A nucleoside derivative; inhibits the proliferation of BHK-21 cells and Ehrlich ascites tumor cells (IC50s = 4 and 6 µM, respectively); reduces virus yield in psuedorabies-infected BHK-21 cells at 1 mM; a product of oxidative DNA damage in vitro
Apexbio Technology LLC 2-Deoxycytidine,1g CAS# 951-77-9
2-Deoxycytidine is a cytidine analog [1]. 2-Deoxycytidine prevents DNA methylation by incorporating itself into newly synthesizing DNA strand. 2-Deoxycytidine also binds to DNA methyltransferase irreversibly and hinders its activity. Thus, 2-deoxycytidine was approved as the most efective demethylating agent for the treatment of cancer [1]. 2-Deoxycytidine at clinically achievable and nontoxic concentrations (≥ 100 μmol/L) protected normal bone marrow progenitor cells against the inhibitory effects of co-administered, high concentrations of 3’-azido-3’-deoxythymidine (AZT) (≥ 10 μmol/L). In normal bone marrow mononuclear cells (BMMC), 2-deoxycytidine also significantly corrected AZT-mediated depletion of intracellular thymidine triphosphate and 2-deoxycytidine triphosphate levels. Furthermore, 2-deoxycytidine reduced the intracellular accumulation of AZT triphosphate and its DNA incorporation in BMMC [2]. Other sizes are also available. Please inqury us for quote.